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·regenerative aesthetics: PRF vs PRP for under-eye rejuvenation

Choosing PRF Over PRP for Med Spa Under-Eye Protocols

Learn why Platelet-Rich Fibrin offers superior longevity and cellular signaling for under-eye rejuvenation compared to traditional PRP treatments.

By Joseph Coram

We are seeing a definitive shift in our clinical protocols toward Platelet-Rich Fibrin for delicate infraorbital rejuvenation. While traditional PRP has served us well, the high-speed centrifugation required often damages cells and utilizes anticoagulants that can sting upon injection. In our practice, we prefer the slow-speed horizontal centrifugation process used for PRF because it preserves a higher concentration of white blood cells and mesenchymal stem cells within a natural fibrin scaffold. This creates a slow-release mechanism for growth factors that lasts significantly longer than the rapid burst provided by PRP. When we sit down to review a new clinic's service menu, we emphasize that PRF acts more like a biological filler, providing a subtle volume correction that complements the regenerative process. This nuance in technology not only improves patient outcomes but also justifies the premium positioning of regenerative services in a competitive aesthetic market.

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