Choosing PRF Over PRP for Under-Eye Rejuvenation Success

We have spent years observing the shift from PRP to PRF for delicate under-eye rejuvenation, and the clinical outcomes consistently favor the fibrin matrix. While traditional PRP provides a quick burst of growth factors, we find that the slower centrifugation speeds used for PRF preserve more white blood cells and mesenchymal stem cells. This results in a natural scaffold that releases healing proteins over several days rather than minutes. From an operator perspective, the lack of anticoagulants in PRF reduces the risk of irritation in the thin tear trough skin. We advise our consulting clients to lead with PRF for this specific indication because the secondary fibrin clot promotes better volume retention and skin thickening. By focusing on these regenerative biological advantages, we can justify the premium positioning of the service while delivering a noticeable reduction in dark circles and fine lines that standard fillers often struggle to address safely.